Below is a list of every paper/ book chapter published with the help of C-SOPS by year. If you require further assistance with locating an article, please contact Doug Hausner.

2006  |  2007  |  2008 |  2009  |  2010 |  2011  |  2012 |  2013  |  2014 |  2015  |  2016 |  2017

Journal Papers

  1. Abbou Oucherif, K, Raina, S, Taylor, LS, Litster, JD, Quantitative Analysis of the Inhibitory Effect of HPMC on Felodipine Crystallization Kinetics Using Population Balance Modeling, Crystal Engineering Communications; featured on the front cover, DOI: 10.1039/C2CE26490K

  2. Acevedo, A., Takhistov, P., Pinzón de la Rosa, C., & Florian, V. (2014). Thermal Gelation of Aqueous Hydroxypropylmethylcellulose Solutions with SDS and Hydrophobic Drug Particles, Carbohydrate Polymers, 102, 74-79,

  3. Afolabi, A., Akinlabi, O., Bilgili, E., A1, Impact of Process Parameters on the Breakage Kinetics of Poorly Water-Soluble Drugs during Wet Media Milling: A Microhydrodynamic View, Volume 51, 2014, Pages 75–86, European Journal of Pharmaceutical Sciences, doi: 10.1016/j.ejps.2013.09.002. Epub 2013 Sep 12.

  4. Akseli, I; Abebe, A; Sprockel, O; Cuitino, AM, Associated Project - Energetic Mechanistic characterization of bilayer tablet formulations, POWDER TECHNOLOGY, DOI:10.1016/j.powtec.2012.05.048 

  5. Austin, J., Gupta, A., McDonnell, R., Reklaitis, G.V., Harris, M.T., The Use of Near-Infrared and Microwave Resonance Sensing to Monitor a Continuous Roller Compaction Process, Journal of Pharmaceutical Science Vol 102(6);1895-1904, 08/2013/J. Pharm. Sci./ (2013), 10.1002/jps.23536.

  6. Austin, J., Harris, M.T., In-Situ Monitoring of the Bulk Density and the Moisture Content of Rapidly Flowing Microcrystalline Cellulose Using a Microwave Resonance Sensor, IEEE Sensors, /IEEE Sensors/ (2013), 10.1109/JSEN.2013.2287991

  7. Austin, J., Rodriquez, S., Sung, P.F., and Harris, M.T., Using Microwaves for the Determination of Moisture Content Independent of Density, Powder Technology, /Powder Technology/ (2013), 10.1016/j.powtec.2012.06.039.

  8. Azad, M., Afolabi, A., Patel, N., Dave, R., Bilgili, E., A1, A8, Preparation of Stable Colloidal Suspensions of Superdisintegrants via Wet Stirred Media Milling, 2013, Particuology, doi: 10.1016/j.partic.2013.07.008

  9. Azad, M.A., Knieke, C., To, D., Davé, R., A8, Preparation of Concentrated Stable Fenofibrate Suspensions via Liquid Antisolvent Precipitation, 0 (2013): 1-11, Drug Development and Industrial Pharmacy, doi:10.3109/03639045.2013.842580

  10. Baird, J.A., Thomas, L.C., Aubuchon, S.R. and Taylor, L. S., C1, Evaluating the Non-isothermal Crystallization Behavior of Organic Molecules from the Undercooled Melt State using Rapid Heat\Cool alorimetry, Crystal Engineering Comm., CrystEngComm. 15(1):111-119, DOI: 10.1039/C2CE26448J

  11. Barraso, D., Oka, S., Muliadi, A., Litster, J., Wassgren, C., Ramachandran, R., Project B4, Population balance model validation and prediction of CQAs for continuous milling processes: Toward QbD in pharmaceutical drug product manufacturing, 2013, Journal of Pharmaceutical Innovation, Vol. 8, No. 3, pp. 147 – 162, 10.1007/s12247-013-9155-0

  12. Barrasso, D., and Ramachandran, R., B7, Multi-component population balance modeling of continuous granulation processes: a parametric study and comparison with experimental trends, Powder Technology, Volume 241, June 2013, Pages 85–97,

  13. Beck, A., Sievens-Figueroa, L., Gärtner, K., Jerez-Rozo, J. I., Romañach, R. J., Bilgili, E., Davé, R. N., A1, A8, Effects of Stabilizers on Particle Redispersion and Dissolution from Polymer Strip Films Containing Liquid Antisolvent Precipitated Griseofulvin Particles, Volume 236, 2013, Pages 37–51. Powder Technology,

  14. Beck, A., Sievens-Figueroa, L., Gärtner, K., Jerez-Rozo, J.I., Romañach, R.J., Michniak-Kohn, B., Bilgili, E, and Davé, R.N., Thrust A, Development of films containing griseofulvin microparticles produced via liquid antisolvent precipitation, Powder Technology, 236 (2013) 37–51, Powder Technology, doi:10.1016/j.powtec.2012.05.047 

  15. Bhakay, A, Azad, M., Bilgili, E., Dave, R., A1, A8, Redispersible Fast Dissolving Nanocomposite Microparticles of Poorly Water-Soluble Drugs, 2013, DOI:10.1016/j.ijpharm.2013.11.059, International Journal of Pharmaceutics, DOI: 10.1016/j.ijpharm.2013.11.059

  16. Bhakay, A., Azad, M., Vizzotti, E., Dave, R., Bilgili, E., A1, A8, Enhanced Recovery and Dissolution of Griseofulvin Nanoparticles from Surfactant-Free Nanocomposite Microparticles Incorporating Wet-Milled Swellable Dispersants, 2013, Drug Development and Industrial Pharmacy, doi: 10.3109/03639045.2013.831442

  17. Blau, G., Orcun,S., Lainez, J.M., Suvannasankha, A., Fausel, C., Anaissie, E.J.,  Reklaitis, G.V.R., D4, Validation of a Novel Approach for Dose Individualization in Pharmacotherapy Using Gabapentin in a Proof of Principles Studey, Pharmacotherapy Vol.33(7);727-735, 07/2013, DOI:10.1002/phar.1267

  18. Blau, G., Orcun,S., Lainez, J.M., Suvannasankha, A., Fausel, C., Anaissie, E.J.,  Reklaitis, G.V.R., D4, Comparison of an Assumption Free Bayesian Approach with Optimal Sampling Schedule to a Maximum A Posteriori Approach for Personalizing Cyclophosphamide Dosing, Pharmacotherapy, DOI:10.1002/phar.1346

  19. Bose, S., Du, Y., Takhistov, P., Michniak-Kohn, B., Formulation optimization and topical delivery of quercetin from solid lipid based nanosystems, Int. J. Pharmaceutics (2013), 441, 56-66. doi: 10.1016/j.ijpharm.2012.12.013. Epub 2012 Dec 20.

  20. Boukouvala, F., Chaudhury, A., Sen, M., Zhou, R., Mioduszewski, L., Ierapetritou, M., Ramachandran, R., D-5, Computer-Aided Flowsheet Simulation of a Pharmaceutical Tablet Manufacturing Process Incorporating Wet Granulation. Journal of Pharmaceutical Innovation, 8, 11, 2013, 10.1007/s12247-012-9143-9.

  21. Boukouvala, F., Gao, Y., Muzzio, F., Ierapetritou, M.G., D-5, Reduced-order discrete element method modeling, Chemical Engineering Science 95, 12-26 (2013),

  22. Boukouvala, F., Ierapetritou, M., D-5, Surrogate-Based Optimization of Expensive Flowsheet Modeling for Continuous Pharmaceutical Manufacturing, Journal of Pharmaceutical Innovation. DOI:10.1007/s12247-013-9154-1

  23. Capece, M., Barrows, J., Davé, R., A1, Controlled Release of Dry-polymer Coated Microparticles, Submitted Dec. 2013, International Journal of Pharmaceutics 

  24. Capece, M., Dave, R., A1, Solventless Polymer Coating of Microparticles, Powder Technology, Submitted Aug.2013, Powder Technology

  25. Capece, M., Dave, R., Bilgili, E., A1, Formulation of a Physically Motivated Breakage Rate Parameter for Dry Ball Milling via the Discrete Element Method, Submitted June 2013, Revision submitted Dec. 2013, AIChE Journal

  26. Capece, M., Dave, R., Bilgili, E., A1, Influence of Non-Linear Breakage Kinetics on the Attainment of Self-Similarity for Dry Milling Processes, Volume 97, 2013, Pages 96–107. Chemical Engineering Science, 

  27. Capece, M., Huang, Z., To, D., Aloia, M., Muchira, C., Davé, R. N., A.B. Yu, A6, Prediction of Porosity from Particle Scale Interactions:  Surface Modification of Fine Cohesive Powders, Submitted June 2013, Revisions submitted Nov 2013, Powder Technology,

  28. Chaffee-Cipich, M., Sturtevant, B., and Beaudoin, S., A6-Associated, Adhesion of Explosives, Analytical Chemistry 85, 5358-5366, DOI: 10.1021/ac302758n

  29. Chaudhury, A., and Ramachandran, R., B7/D5, Integrated population balance model development and validation of a granulation process, Particulate Science & Technology, Volume 31, Issue 4, 2013 DOI:10.1080/02726351.2013.767295

  30. Chaudhury, A., Kapadia, A., Barrasso, D., Prakash, A.V., and Ramachandran, R., B7/D5, An Extended Cell-average Technique for Multi-Dimensional Population Balance Models describing Aggregation and Breakage, Advanced Powder Technology, Volume 24, Issue 6, November 2013, Pages 962–971,

  31. Chaudhury, A., Oseledets, I., Ramachandran, R., B7/D5, A computationally efficient technique for the solution of multi-dimensional PBMs of granulation via tensor decomposition, Computers & Chemical Engineering, Volume 61, 11 February 2014, Pages 234–244,

  32. Chaudhury, A., Wu, H., Khan, M., Ramachandran, R., B7/D5, A mechanistic population balance model for granulation processes: Effect of process and formulation parameters, Chemical Engineering Science, Volume 107, 7 April 2014, Pages 76–92,

  33. Chen, Y., Pekny, J.F., Reklaitis, G.V.R., D4, Integrated Planning and Optimization of Clinical Trial Supply Chain System with Risk Pooling, Industrial & Engineering Chemistry Research Vol.52(1);152-165,  01/2013, DOI:10.1021ie300823b

  34. Dalvi, S., Azad, M., Davé, R.N., Thrust A, Precipitation and Stabilization of Ultrafine Particles of Fenofibrate in Aqueous Suspensions by RESOLV, 236 (2013) 75–84, Powder Technology, doi:10.1016/j.powtec.2012.05.038

  35. Dave, RN; Bilgili, E; Jallo, L; Cuitino, A., B and C Thrusts, Special issue on pharmaceutical powders: Towards developing understanding of the influence of materials and processes on product performance, POWDER TECHNOLOGY, DOI:10.1016/j.powtec.2012.09.005 

  36. Deng, X., Davé, R.N., A6, Dynamic simulation of particle packing influenced by size, aspect ratio and surface energy, Granular Matter (2013), special issue, Page 1-15. Granular Matter, DOI 10.1007/s10035-013-0413-0

  37. El Hagrasy A.S., Cruise P., Jones, I., and Litster, J. D., B7, In-line Size Monitoring of a Twin Screw Granulation Process Using High-Speed Imaging, Pharm Innov, DOI 10.1007/s12247-013-9149-y

  38. El Hagrasy, A., and Litster, JD, B7, Granulation Rate Processes in the Kneading Elements of a Twin Screw Granulator, AIChE J., DOI:10.1002/aic.14180 

  39. El Hagrasy, A., Cruise, P, Jones, I., and Litster, JD, Commercialization In-Line Size Monitoring of a Twin Screw Granulation Process Using High-Speed Imaging, Pharm Innov, June 2013, DOI: 10.1007/s12247-013-9149-y

  40. El Hagrasy, A., Hennenkamp, J.R., Burke, M.D., Cartwright, J.J., and Litster, JD, Commercialization Twin Screw Wet Granulation; Influence of Formulation Parameters on Granule Properties and Growth Behavior, Powder Technology Vol. 238(SI); 108-115 April 2013, DOI 10.1016/j.powtec.2012.04.035

  41. Emady, HN, Kayrak-Talay, D, and Litster, JD, Modeling the granule formation mechanism from single drop impact on a powder bed, J.Colloid Interface Science, 393, 369-376, doi: 10.1016/j.jcis.2012.10.038. Epub 2012 Oct 25. PMID: 23153678 [PubMed]

  42. Florian, M., Velazquez, C., Mendez, R., B2, New Continuous Tumble Mixer Characterization, Powder Technology, in review (2013), Powder Technology, accepted for publication Feb/7/2014

  43. Gao, Y., Boukouvala, F., Engisch, W., Meng, W., Muzzio, F., Ierapetritou, M., D-5, Improving Continuous Powder Blending Performance Using Projection to Latent Structures Regression, Journal of Pharmaceutical Innovation. DOI: 10.1007/s12247-013-9152-3

  44. Gao, Y., Ierapetritou, M.G., and Muzzio, F.J., D-5, Determination of the Confidence Interval of the Relative Standard Deviation Using Convolution. Journal of Pharmaceutical Innovation, DOI: 10.1007/s12247-012-9144-8

  45. Gao, Y., Ierapetritou, M.G., and Muzzio, F.J., D-5, Scale-up strategy for continuous powder blending process, Powder Technology, 235(0), 55, 2013,

  46. Gao, YJ; Glasser, BJ; Ierapetritou, MG; Cuitino, A; Muzzio, FJ; Beeckman, JW; Fassbender, NA; Borghard, WG, Associated Project – Calcination, Measurement of Residence Time Distribution in a Rotary Calciner, AICHE JOURNAL, DOI:10.1002/aic.14175

  47. Gao, Y., Glasser, B.L., Ierapetritou, M.G., Cuitino, A.. Muzzio, F.J., Beeckman, J., Fassbender, N., Borghard, W., Determination of Residence Time Distribution in Rotary Calciner, AIChE Journal, 59(11), 4068- 4076, 2013. 

  48. Gao, Y., Muzzio, F.J., Ierapetritou, M., Scale-up strategy for continuous powder blending process, Powder Tech. 235, 55-69, 2013.

  49. Gao, Y., Ierapetritou, M.G., Muzzio, F.J., Estimation of the confidence interval of the RSD measurement in pharmaceutical manufacturing,  Journal of Pharmaceutical Innovation, 8(2), 72-82, 2013 

  50. Ghoroi, C., Gurumurthy, L., McDaniel, D.J., Jallo, L., Davé, R.N., Thrust A, Multi-faceted characterization of flow, packing and fluidization properties of pharmaceutical powders for discerning the influence of surface modification, 236 (2013), 63–74., Powder Technology, doi:10.1016/j.powtec.2012.05.039

  51. Ghoroi, C., Han, X., To, D., Jallo, L., Gurumurthy, L., Davé, R.N., Thrust A, Dispersion of ultrafine powders through surface modification or rapid expansion, Special Issue (Ed. F. Saito), 85, pp. 11-24, 2013, Chemical Engineering Science, doi: 10.1016/j.ces.2012.02.038

  52. Grigorov, P.I., Glasser, B.J., and Muzzio, F.J., Formulation and Manufacture of Pharmaceuticals by Fluidized Bed Impregnation of Active Pharmaceutical Ingredients onto Porous Carriers, Yes, AIChE Journal, 59, 4538–4552, 2013

  53. Giraldo L.M., Trasi, N.S., Taylor, L.S., Project C1, Role of surfactants in influencing crystal growth rates from amorphous Celecoxib, Int. Journal. Of Pharmaceutics, In press

  54. Gulak, Y; Braido, D; Cuitino, A., C4-C5, Capillary models of solvent diffusion, Chemical Engineering Science, DOI: 10.1016/j.ces.2013.07.016 

  55. Gupta, A., Giridhar, A., Venkatasubramanian, V., and Reklaitis, G.V., D4, Intelligent Alarm Management Applied to Continuous Pharmaceutical Tablet Manufacturing: An Integrated Approach, Ind. Eng. Chem. Res., 2013, 52 (35), pp 12357–12368, DOI: 10.1021/ie3035042

  56. Hamad, M.L., Engen, W., Morris, K.R., Impact of hydration state and molecular oxygen on the chemical stability of levothyroxine sodium, Pharmaceutical Development and Technology, ISSN:1083-7450 (print), 1097-9867 (electronic), PMID: 24295156 [PubMed - as supplied by publisher], ), doi:10.3109/10837450.2013.862635

  57. Han, X., Jallo, L., To, D., Ghoroi, C., Davé, R., A6, Passivation of high surface energy sites of milled ibuprofen crystals via dry coating, Vol. 7, 1–15, Journal of Pharmaceutical Sciences

  58. Heigl, N., Koller, D.M., Glasser, B.J., Muzzio, F.J., Khinast, J.G., Quantitative on-line vs. off-line NIR analysis of fluidized bed drying with consideration of the spectral background, European Journal of Pharmaceutics and Biopharmaceutics, Yes, 85, 1064-1074, 2013 

  59. Harrison A. J., Bilgili, E. A., Beaudoin, S. P. and Taylor, L. S., C1, Atomic force microscope infrared spectroscopy of griseofulvin nanocrystals, Analytical Chemistry 85(23):11449-11455, DOI: 10.1021/ac4025889, October (2013)

  60. Hirshfield, L., Giridhar, A., Taylor, L.S., Harris, M.T., Reklaitis, G.V., TB3, Dropwise Additive Manufacturing of Pharmaceutical Products for Solvent-Based Dosage Forms, Journal of Pharmaceutical Sciences, DOI: 10.1002/jps.23803

  61. Hsu, H-Y, Toth, S. J., Simpson, G. J., Taylor, L. S., Harris, M. T., C1, Effect of Substrates on Naproxen\Polyvinylpyrrolidone Solid Dispersions Formed via the Drop Printing Technique, Journal of Pharmaceutical Science; 102(2):638-648, doi: 10.1002/jps.23397. Epub 2012 Dec 5, PMID: 23225152 [PubMed - indexed for MEDLINE]

  62. Hu, D., Haware, R.V., Hamad, M.L., Morris, K.R., A-7, Characterization of critical physical and mechanical properties of freeze dried grape powder for development of a clinical patient delivery system, Pharmaceutical Development and Technology Vol 18(1);146-155   02/2013, DOI:10.3109/10837450.2012.659257

  63. Huang, Z., Scicolone, J.V., Gurumuthy, L., Davé, R.N., A6, Flow and Bulk Density Enhancements of Pharmaceutical Powders using a Conical Screen Mill: A Continuous Dry Coating Device, Submitted Nov 2013, Chemical Engineering Science

  64. Järvinen, M., Paaso, J., Paavola, M., Leiviskä, K., Juuti, M., Muzzio, F., Järvinen, K., Continuous direct tablet compression: effects of impeller rotation rate, total feed rate and drug content on the tablet properties and drug release, DDIP, 39(11):1802-1808, 2013

  65. Kanwal, A., Wang, S.C., Ying, Y., Cohen, R., Laksmanan, S., Patlolla, A., Iqbal, Z., Thomas, G., Farrow, R., C3, A Discrete Nanoscalable Biofuel Cell - accepted December 2013, Electrochemistry Communications, 

  66. Kaspar, O., Tokarova, V., Oka, S., Sowrirajan, K., Ramachandran, R., Stepanek, F., B7, Combined UV/vis and micro-tomography investigation of acetaminophen dissolution from granules, International Journal of Pharmaceutics, 2013 Dec 31;458(2):272-81, PMID: 24409518 [PubMed - in process]

  67. Kim, K., Shen, D., Nagy, ZK., Braatz, R., Wiener’s Polynomial Chaos for the Analysis and Control on nonlinear Synamical Systems with Probabilistic Uncertainties, IEEE Control Systems Magazine Vol.33(5);58-67 10.2013, DOI:10.1109/MCS.2013.2270410

  68. Knieke, A., Azad, M. A., Davé, R. N., Bilgili, E., A1, A Study of the Physical Stability of Wet Media-Milled Fenofibrate Suspensions Using Dynamic Equilibrium Curves, Volume 91, 2013, Pages 1245–1258. Chemical Engineering Research and Design, 

  69. Knieke, A., Rawtani, A., Davé, R.N., Thrust A, Concentrated fenofibrate nanoparticle suspensions from melt emulsification for enhanced drug dissolution, Accepted Sep 2013, Chemical Engineering & Technology, DOI: 10.1002/ceat.201300355

  70. Kottala, N; Abebe, A; Sprockel, O; Akseli, I; Nikfar, F; Cuitino, AM, Associated Project – Energetic Characterization of interfacial strength of layered powder-compacted solids, POWDER TECHNOLOGY, DOI: 10.1016/j.powtec.2012.12.028 

  71. Koynov, A; Romanski, F; Cuitino, AM, C4, Effects of particle size disparity on the compaction behavior of binary mixtures of pharmaceutical powders, Powder Technology, DOI:10.1016/j.powtec.2012.07.046 

  72. Kumar, R., and Wassgren, C., Commercialization, Angular circulation speed of tablets in a vibratory tablet coating pan, AAPS PharmSciTech, Vol. 14, No. 1, pp. 339 – 351, doi: 10.1208/s12249-012-9917-x. Epub 2013 Jan 17, PMID: 23325382 [PubMed - indexed for MEDLINE] PMCID: PMC3581638

  73. Kuriyan, K., and Reklaitis, G.V., Creating Shared Resources for Pharmaceutical Technology Education-Simulation Tools, Education for Chemical Engineers, Vol. 8, pp. e124-e131, December 2013, DOI: 10.1016/j.ece.2013.10.002

  74. Lainez, J.M., Reklaitis, G.V.R., D4, A Stochastic Optimization approach for the design of Individualized Dosage Regimens, AIChE Journal, Vol 59(9);3296-3307, 09/2013, DOI:10.1002/aic.14100 

  75. Li, J., Freireich, B., process in a paddle mixer/coater: The effect of particle size distribution on particle segregation and coating uniformity, Chem.Eng.Sci., 95, 203–210

  76. Li, J., Freireich, B., Wassgren, C., and Litster, JD, Experimental Validation of a 2-D Population Balance Model for Spray Coating Processes, Chem Eng Sci, 95, 360-365, DOI: 10.1016/j.ces.2012.02.036 

  77. Liu, LX, Marziano, I, Bentham, AC, Litster, JD, White, ET, and Howes, T., B4, Influence of particle size on the direct compression of ibuprofen and its binary mixtures, Powder Technolog; 66-73,

  78. Liu, X., Muzzio, F.J., Khinast, J.G., Glasser, B.J., Fluidized Bed Drying of Pharmaceutical Materials: Moisture Measurement and Effects of Particle Size, American Pharmaceutical Review, 4, (2013)

  79. Łuczak, A., Jallo, L.J., Dave, R.N., Iqbal, Z., Thrust A, Polymorph Stabilization in Processed Acetaminophen Powders, 236 (2013) 52–62, Powder Technology, doi:10.1016/j.powtec.2012.05.046

  80. Llusa, M., Pingali, K., and Muzzio, F.J., Effects of type of microcrystalline cellulose and blend flowability on the homogeneity of acetaminophen, Yes, Drug  Development and Industrial Pharmacy, 39, 1464-1475, 2013

  81. Mateo, D., Muzzio, F., Mendez, R., B1, Particle size segregation promoted by powder flow in confined space: The die filling process case, Powder Technology, in review (2013), Powder Technology

  82. Muliadi, AR, Litster, JD and Wassgren, CR, B4, Validation of 3-D finite element analysis for predicting the density distribution 6 of roll compacted pharmaceutical powder, Powder Technology, DOI:10.1016/j.powtec.2012.12.023 

  83. Nair, AR; Mason, BA; Groven, LJ; Son, SF; Strachan, A; Cuitino, AM, Associated Project – Energetic, Micro-RVE modeling of mechanistic response in porous intermetallics subject to weak and moderate impact loading, INTERNATIONAL JOURNAL OF PLASTICITY, DOI:10.1016/j.ijplas.2013.06.009

  84. Obregon, L., Quinones, L., Velazquez, C., Model predictive control of a fluidized bed dryer with an inline NIR as moisture sensor, Control Engineering Practice,

  85. Osorio, J.G., Stuessy, G., Kemeny, G.J., Muzzio, F.J., Characterization of Pharmaceutical Powder Blends Using In Situ Near-Infrared, Chemical Imaging, accepted, Chemical Engineering Science, 2013

  86. Osorio, J.G., and Muzzio, F.J., Effects of powder flow properties on capsule filling weight uniformity, Drug Development and Industrial Pharmacy., 39, 1464-1475, 2013

  87. Prakash, A.V., Chaudhury, A., and Ramachandran, R., D5, Parallel simulation of population balance model-based particulate processes using multi-core CPUs and GPUs, Modelling and Simulation, Volume 2013 (2013), Article ID 475478, 16 pages, 

  88. Prakash, A.V., Chaudhury, A., D. Barrasso and R. Ramachandran, D5, Simulation of population balance model-based particulate processes via parallel and distributed computing. Chemical Engineering Research & Design, Volume 91, Issue 7, July 2013, Pages 1259–1271,

  89. Ravikumar, C., Li, M., Afolabi, A., Yaragudi, N.K.R., Dave, R.N., Bilgili, E., A1, Sub-100 nm Drug Particle Suspensions with Low Media Contamination Prepared via an Intensified Wet Milling Process, Dec. 2013, Submitted, International Journal of Pharmaceutics

  90. Rogers, A.J., Hashemi, A., Ierapetritou, M.G., D-5, Modeling of Particulate Processes for the Continuous Manufacture of Solid-Based Pharmaceutical Dosage Forms, Processes. 1(2) 67-127 (2013), doi:10.3390/pr1020067

  91. Rogers, A.J., Inamdar, C., Ierapetritou, M.G., D-5, An Integrated Approach to Simulation of Pharmaceutical Processes for Solid Drug Manufacture, Ind. Eng. Chem. Res., DOI: 10.1021/ie401344a

  92. Sen, M., Chaudhury, A., John, J., Singh, R., Ramachandran, R., D5, Multi-scale flowsheet simulation of an integrated continuous purification-downstream pharmaceutical manufacturing process, International Journal of Pharmaceutics, Volume 445, Issues 1–2, 10 March 2013, Pages 29–38,

  93. Sen, M., Dubey, A., Singh, R., Ramachandran, R., D5, Hybrid PBM-DEM simulation and validation of a continuous mixing process, Journal of Powder Technology,

  94. Sen, M., Rogers, A., Singh, R., Chaudhury, A., John, J., Ierapetritou, M., and Ramachandra, R., D5, Flowsheet modeling and optimization of an integrated pharmaceutical purification-processing manufacturing operation, Chemical Engineering Science, Volume 102, 11 October 2013, Pages 56–66,

  95. Sievens-Figueroa, L., Pandya, N., Bhakay, A., Keyvan, G., Michniak-Kohn, B., Bilgili, E., Davé, R.N., TB2, Using USP I and USP IV for discriminating dissolution rates of nano and micro particle loaded pharmaceutical strip-films, Vol 13, 4, Dec 2012, Pages 1473–1482, AAPS PharmSciTech, doi:10.1208/s12249-012-9875-3

  96. Singh, R., Ierapetritou, M., and Ramachandran, R., D2, System-wide hybrid MPC-PID control of a continuous pharmaceutical tablet manufacturing process via direct compaction, Eur Journal of Pharmaceutics and Biopharmaceutics, Volume 85, Issue 3, Part B, November 2013, Pages 1164–1182,

  97. Singh, R., Sahay, A., Oka, S., Liu, X., Ramachandran, R., Ierapetritou, M., Muzzio, F., D-2, D-5,    Online monitoring, advanced control and operation of robust continuous pharmaceutical tablet manufacturing process. BioPharma magazine Asia. 2, 2013.

  98. Singh, R., Sahay, A., Muzzio, F., Ierapetritou, M., Ramachandran, R, Systematic framework for onsite design and implementation of a control system in the continuous tablet manufacturing process, submitted, Computers and Chemical Engineering Journal, 2013.

  99. Smith, K.M. Butterbaugh, J.W., and Beaudoin, S., A6-Associated, Effects of Varying Surface Film Thickness on Particle Adhesion in Semiconductor Material-Based Systems, Journal of the Elctrochemical Society, doi:10.1149/1.3630850

  100. Susarla, R., Sievens-Figueroa, L., Bhakay, A., Shen, Y., Jerez-Rozo, J. L., Engen, W., Khusid, B., Biligili, E., Romanach, R., Morris, K.R., Michniak-Kohn, B., Dave, R. N., Fast drying of biocompatible polymer films loaded with poorly water soluble drugs nano-particles via low temperature forced convection, Int. J. Pharm. (2013), 445, 93-103,

  101. Van Eerdenbrugh, B., Raina, S.A., Hsieh, Y-L., Augustinjns, P. and Taylor, L.S., C1, Classification of the Crystallization Behavior of Amorphous Active Pharmaceutical Ingredients in Aqueous Environments, Pharmaceutical Research- accepted, 10.1007/s11095-013-1216-z

  102. Vasilenko, A., Koynov, S., Glasser, B.J., Muzzio, F., Role of Consolidation State in the Measurement of Bulk Density and Cohesion, Powder
    Technology, 239, 366-373 (2013)

  103. Wu, A., Beck, C., Ying, Y., Federici, J., and Iqbal, Z., C3, Thermochromism in Polydiacetylene-ZnO Nanocomposites - accepted August 2013, Journal of Physical Chemistry C,

  104. Wu, A., Gu, Y., Beck, C., Iqbal, Z., Federici, J., C3, Reversible chromatic sensor fabricated by inkjet printing TCDA-ZnO on a paper substrate -accepted November 2013, Sensors and Actuators,

  105. Yi, G., Reklaitis, G.V.R., D4, Optimal Design of Generalized Batch-Storage Network Considering Shortage Costs, AIChE Journal, Vol 59(7); 2454-2470  07/2013, DOI:10.1002/aic.14012

  106. Ying, Y., Afolabi, A., Bilgili E., and Iqbal, Z., C3, In-line Raman Spectroscopic Monitoring of Size Reduction during Wet Media Milling of BCS Class II Drugs - submitted Dec 2013, Applied Spectroscopy

  107. Youngren, S.R., Mulik, R., Jun, B., Hoffman, P.R., Morris, K.R., Chougule, M.B., A-7, Freeze-Dried Targeted Mannosylated Selenium-Loaded Nanoliposomes:Development and Evalation, AAPS Pharmscitech Vol.1(3);1012-1024  09/2013, DOI:10.1201/s12249-013-9988-3

  108. Vanarase, A.U., Osorio, J.G., Muzzio F.J., Effects of powder flow properties and shear environment on the performance of continuous mixing of pharmaceutical powders, Powder Technology. 246, 63-72 (2013) 

  109. Vanarase, A.U., Jarvinen, M., Paaso, J., Osorio, J.G., Muzzio F.J., Development of a methodology to estimate error in the in-line concentration measurements in a continuous powder mixing process, Powder Technology. 241, 263–271 (2013). 

  110. Zarate, N., Harrison, A., Litster, J., Beaudoin, S., Project A6, Effect of relative humidity on onset of capillary forces for rough surfaces, Journal of Colloid and Interface Science Vol 411; 265-272 12/2013, DOI: 10.1016/j.jcis.2013.05.048

  111. Zhang, J., Ying, Y., Pielecha-Safira, B., Bilgili, E.A., Ramachandran, R., Romañach, R.J., Davé, R.N., Iqbal, Z., C3, Raman spectroscopy for in-line and off-line quantification of poorly soluble drugs in strip films, Submitted Dec.2013, International Journal of Pharmaceutics

  112. Zhou, Q., Toth, S.J., Simpson, G.J., Hsu H-Y., Harris, M.T., Taylor, L.S., Project C1, Crystallization and Dissolution Behavior of Naproxen\Polyethylene Glycol Solid Dispersions, Journal of Physical Chemistry Vol 117(5);1494-1500 02/2013, DOI:10.1021/jp3106716

  113. Zhu, Q, Toth, S, Simpson, GJ, Hsu, HY, Taylor, LS, Harris, MT, C1, Crystallization and Dissolution Behavior of Naproxen\Polyethylene Glycol Solid Dispersions, Journal of Physical Chemistry Vol 117(5); 1494-1500 02/2013, DOI:10.1021/jp3106716

Books & Book Chapters

  1. -

Publications from Associated Projects

  1. Knieke, C., Rawtani, A., Davé, R. N., “Concentrated fenofibrate nanoparticle suspensions from melt emulsification for enhanced drug dissolution,” Chemical Engineering & Technology, accepted September 2013, online, December 3, 2013, DOI: 10.1002/ceat.201300355. (ERC Associated Project)

  2. Capece, M., Barrows, J., Davé, R., “Controlled Release of Dry polymer Coated Microparticles,” International Journal of Pharmaceutics, submitted December 2013, in review. (ERC Associated Project)

  3. Beck, C., Sievens Figueroa, L., Gärtner, K., Jerez Rozo, J. I., Romañach, R.J., Michniak Kohn, B., Bilgili, E., and Davé, R. N., “Development of films containing griseofulvin microparticles produced via liquid antisolvent precipitation,” Powder Technology, 236 (2013) 37–51. doi:10.1016/j.powtec.2012.05.047

  4. Scicolone, J., Lepek, D., Louie L., and Davé, R. N., “Fluidization and Mixing of Nanoparticle Agglomerates Assisted via Magnetic Impaction,” Journal of Nanoparticle Research, 15:1434, 2013. DOI 10.1007/s1105101314347

  5. Afolabi, A., Akinlabi, O., Bilgili, E., “Impact of Process Parameters on the Breakage Kinetics of Poorly Water‐Soluble Drugs during Wet Media Milling: A Microhydrodynamic View,” Euro. J. of Pharmaceutical Sciences, 51, 2014, Pages 75-86.

  6. Farrell, S. and J. Vernengo, “Introducing Students to Drug Delivery from Swellable Matrices,” Advances in Engineering Education, (in revision)

  7. Ghoroi, C., Gurumurthy, L., McDaniel, D. J., Jallo, L., Davé, R. N., “Multi‐faceted characterization of flow, packing and fluidization properties of pharmaceutical powders for discerning the influence of surface modification,” Powder Technology, 236 (2013), 63–74. doi:10.1016/j.powtec.2012.05.039.

  8. Azad, M. A., Afolabi, A., Patel, N., Davé, R., Bilgili, E., “Preparation of Stable Colloidal Suspensions of Superdisintegrants via Wet Stirred Media Milling,” Particulogy, accepted July 2013, online, September 2013. doi: 10.1016/j.partic.2013.07.008

  9. Sievens Figueroa, L., Pandya, N., Bhakay, A., Keyvan, G., Michniak Kohn, B., Bilgili, E., Davé, R.N., “Using USP I and USP IV for discriminating dissolution rates of nano and micro particle loaded pharmaceutical strip films,” AAPS PharmSciTech, S 13 (4), pp. 1473-1482, 2013; DOI:10.1208/s1224901298753.