Webinar Series Registration: Enabling real time release testing by NIR prediction of dissolution of
C-SOPS Webinar Series Presents Enabling real time release testing by NIR
prediction of dissolution of tablets by
Continuous Direct Compression (CDC) Pallavi Pawar, Ph.D.
Wednesday July 27th 2016 @ 1PM EST The methodology enables real-time release testing. Tablets were made at a target drug concentration of 9% APAP, containing 90% lactose and 1% Magnesium Stearate, and at a target compression force of 24 kN. A model for predicting dissolution profiles was developed using a
Webinar Series: Batch vs. Continuous Blending of Segregating Blends and the “Oka Ratio”
Binary powder mixtures with variable segregation tendencies were “mixed” in a tumbling batch blender and in a continuous convective tubular blender. The degree of homogeneity of the final blend obtained from the continuous blender was found to be much higher than that from the batch V-blender. A direct relationship was observed between the segregation index of freely-flowing mixtures and a new material property metric, the “Oka Ratio”, defined as the ratio of the median parti
